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The most common mode of nicotine exposure in animals is ingestion- especially of nicotine gum and chewing tobacco due to the palatability of these products

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Sasaki M, Yamaura C, and Ohara-Nemoto Y, et al (2005) Streptococcus anginosus infection in oral cancer and its infection route Oral Dis 11 151156 PMID: 15888105 72

However, this phase is temporary